This month, I presented the Clinical Trial Risk Tool at the Plotly Dash in Action webinar. I was interviewed by Plotly’s Community Manager Adam Schroeder. You can watch the relevant part of the webinar below.
The Clinical Trial Risk Tool was one of four interactive apps presented as part of the webinar. The speakers at the webinar were:
Screenshot of Matteo Trachsel’s Thermoplan dashboard which calculates the carbon footprint of coffee machine usage.
Screenshot of Agah Karakuzu’s dashboard which allows neuroscientists to assess the reproducibility of T1 values across different sites and vendors where researchers used the same research protocol. (T1 is the time it takes water molecules in the brain to return to their original state following a magnetic pulse).
If you would like to cite the tool alone, you can cite:
Wood TA and McNair D. Clinical Trial Risk Tool: software application using natural language processing to identify the risk of trial uninformativeness. Gates Open Res 2023, 7:56 doi: 10.12688/gatesopenres.14416.1.
A BibTeX entry for LaTeX users is
@article{Wood_2023, doi = {10.12688/gatesopenres.14416.1}, url = {https://doi.org/10.12688%2Fgatesopenres.14416.1}, year = 2023, month = {apr}, publisher = {F1000 Research Ltd}, volume = {7}, pages = {56}, author = {Thomas A Wood and Douglas McNair}, title = {Clinical Trial Risk Tool: software application using natural language processing to identify the risk of trial uninformativeness}, journal = {Gates Open Research} }
Creating clinical trial budgets from protocols Creating a clinical trial budget is a fiddly and time consuming process. The playbook for running the clinical trial is a document called the protocol. You can find examples of protocols here. The protocol states how many participants will take part in the trial and also what visits and procedures will take place. Above: a protocol. Source: NCT04128579 A clinical trial manager must read the protocol and look for all pieces of information in the protocol that is relevant to the budget, in particular the Schedule of Events (also called Schedule of Assessments or Schedule of Activities), which is a table or series of tables which indicate which procedures and assessments will take place on which the visits.
We have improved the Clinical Trial Risk Tool in the last 6 months, making it more user friendly and taking on board the feedback that we’ve received. We’ve improved the accuracy of the machine learning components too. The tool now outputs its key figures such as risk levels and estimated cost in easily readable cards, so you can see at a glance the key takeaways from your protocol: The risk factors are now organised into collapsible categories, so you can explore them easily without an information overload.
Guest post by Safeer Khan, Lecturer at Department of Pharmaceutical Sciences, Government College University, Lahore, Pakistan Introduction The success of a clinical trial is strongly dependent on the structure and coordination of the teams managing it. Given the high stakes and significant impact of every decision made during the trial, it is essential for each team member to collaborate efficiently in order to meet strict deadlines, comply with regulations, and ensure reliable results.
