Natural language processing is becoming ever more important in research. The explosion in interest in LLMs is sparking many opportunities to analyse text data in healthcare, social sciences, and other areas.
We’re proud to announce that the Clinical Trial Risk Tool has been selected as a winner of the Plotly Dash Example Apps Challenge (2023), out of 25 amazing apps submitted by the community.
Funded by the Bill and Melinda Gates Foundation, this app uses natural language processing, Plotly Dash, and the spaCy and Scikit-Learn libraries to calculate the risk of a clinical trial failing to deliver informative results. It reads the trial protocol and identifies key features from the text which are fed into a risk model.
Join Plotly’s webinar to see the tool in action! https://tinyurl.com/4zd3emkr
You can try the new version of the app at: https://clinicaltrialrisk.org/tool
You can try version 1.0 of the app (using Plotly Dash) at: https://clinicaltrialrisk.org/tool/login?guest=true/.
Wood TA and McNair D. Clinical Trial Risk Tool: software application using natural language processing to identify the risk of trial uninformativeness. Gates Open Res 2023, 7:56 (https://doi.org/10.12688/gatesopenres.14416.1).
Over the years, the overall cost of the drug development process has been exponentially increasing, prompting the adoption and use of adaptive clinical trial design software. Though there are practical difficulties and barriers in implementing clinical trial solutions, these problems are adequately addressed to overcome these issues as they arise. With advancements in software technologies, further improvements are being made to the software’s adaptive clinical trial design. Despite these progresses, just only a handful of well-established software with various types of clinical trial adaptations is currently available.
A clinical trial protocol is a document which serves as the step-by-step playbook for running the trial. The clinical trial protocol guides the study researchers to run the clinical trial effectively within a stipulated period. The prime focus of the clinical trial protocol is to ensure patients’ safety and data security. [1, 2] As the clinical trial protocol is an essential document for the seamless execution of the clinical trial, reviewing (peer-reviewing) the protocol is essential to ensure the scientific validity/viability/quality of the protocol.
Guest post by Safeer Khan, Lecturer at Department of Pharmaceutical Sciences, Government College University, Lahore, Pakistan Introduction As we move toward 2025, clinical trial regulations are undergoing significant transformation. This shift is being fueled by technological advancements, changing healthcare needs, and an increasing emphasis on transparency and patient safety. In this post, we will explore the key clinical trial regulations shaping the clinical trial landscape, the challenges professionals face, and the strategies they must adopt to navigate this ever-evolving environment.
